Sunday, 20 March 2011

Stockley's Drug Interactions 7th Edition

http://rapidshare.com/files/78907124/Stockely_drug_interaction.zipStockley's Drug Interactions 7th Edition

Stockley's Drug Interactions, produced within the Martindale Editorial Team under Karen Baxter, remains the world's most comprehensive and authoritative reference book on drug interactions.
Contains detailed yet concise monographs

Covers interactions between therapeutic drugs, proprietary medicines, herbal medicines, foods, drinks, pesticides and some drugs of abuse

Based on published sources and fully referenced

A typical monograph contains a summary, clinical evidence for the interactions under discussion, the probable mechanism, clinical importance and management

Covers over 14,000 drug interactions

Contains over 2,800 monographs

Includes 17,600 references


Stockley's Drug Interactions provides the busy healthcare professional with quick and easy access to clinically relevant, evaluated and evidence-based information on drug interactions.
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Drug-Drug Interactions: Scientific and Regulatory Perspectives, Volume 43 (Advances in Pharmacology)


Drug-Drug Interactions: Scientific and Regulatory Perspectives, Volume 43 (Advances in Pharmacology)


Drug–Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug–drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug–drug interactions, the prediction of drug–drug interaction potential of new drugs, and the avoidance of clinically significant drug–drug interaction in patients.
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Key Features


* Provides useful references on the science of drug-drug interactions
* Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint
* Contains original data from academic and industrial laboratories
* Presents an overview of regulatory agency positions

http://rapidshare.com/files/275421125/tdrugdrug_interv43.zip
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Saturday, 19 March 2011

Handbook of Drug Metabolism


Handbook of Drug Metabolism
http://rapidshare.com/files/144844393/thb_drug_metabo.zip

Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.
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A Handbook of Bioanalysis and Drug Metabolism




Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting until now.
A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drugdrug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills.

This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.
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Clinical Epidemiology The Essentials

Clinical Epidemiology The Essentials
Authors: Robert H. Fletcher, Suzanne W. Fletcher

This introduction to epidemiology helps medical, nursing, and pharmacy students develop a system to observe and assess outcomes in similar patient types, and then apply this knowledge of outcomes to improve future patient care. The Fourth Edition has been redesigned to enhance understanding with new illustrations, pedagogical tools, examples, and summary boxes.

According to a faculty member at the University of North Carolina, "This is one of the few books truly written for students of clinical epidemiology...I've used it in the past and would do so in the future. The book is comprehensive and takes a practical approach to explaining important topics."
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Thursday, 17 March 2011

Impurities Evaluation of Pharmaceuticals


Impurities Evaluation of Pharmaceuticals

Filling a gap in the pharmaceutical literature, this unique guide addresses the development of targeted methodologies to monitor impurities in pharmaceutical compounds and drug products. Furnishes physicochemical protocols to determine the purity of pharmaceutical compounds fully before pharmacological and toxicological studies begin! Providing a clear definition of the subject, Impurities Evaluation of Pharmaceuticals introduces various techniques for isolating and characterizing impurities presents guidelines to evaluate stability using kinetic studies shows how to develop stability-indicating methodologies details various methods that require minimal sample prepreparation gives regulatory perspectives on chiral impurities and more! Containing important literature citations and offering an invaluable list of applications, Impurities Evaluation of Pharmaceuticals is an outstanding resource for pharmacists and pharmacologists, clinical microbiologists, quality assurance and production managers in the pharmaceutical industry, analytical chemists and biochemists, pharmaceutical regulatory personnel, and upper-level undergraduate, graduate, and continuing-education students in these disciplines.

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Pharmaceutical Drug Analysis


Pharmaceutical Drug Analysis

‘Pharmaceutical Drug Analysis’ will prove to be a valuable and indispensable guide to
those working in Research & Development Laboratories, Quality Assurance Laboratories as well as Drug Testing Laboratories where either new products are being developed or routine analyses are carried out. Academicians and researchers engaged in the evaluation of pharmaceutical drug substances either in pure or dosage forms will also enormously benefit from ‘Pharmaceutical Drug Analysis’ by virtue of its ultimate goal of maintaining very high standards of quantitative analysis.
Finally, I wish to record here my special thanks to the numerous colleagues and friends who have not only extended their invaluable help by providing me with relevant sources of material but also by taking an active participation in the discussion of various chapters.
It is hoped that ‘Pharmaceutical Drug Analysis’ will soon prove to be an invaluable guide to both undergraduate and postgraduate students and to my esteemed colleagues in the teaching profession. Those working in Research & Development Laboratories, Quality Assurance Laboratories and Drug Testing laboratories will also find the book helpful in solving many of their intricate problems.


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